The Benefits of Nrf2 Activation

health care medicine Oct 23, 2018

I know many of us take supplements (myself included), and I’m not saying that’s a bad thing. But what if you could activate your cells to switch on their own innate healing capabilities? What if you could reduce oxidative stress by an average of 40% in a month thus dramatically reducing inflammation, open up detoxification pathways, regulate healthy gene expression and boost your body’s natural glutathione production by 300%? All with a simple, natural formula. The benefits of Nrf2 activation extend from preventive medicine and anti-aging, all the way to helping the body recover from chronic health conditions.


I have spent the past few months researching Nrf1 and Nrf2 activation – it’s absolutely fascinating to me. I have also been working with my patients on this, and seeing very positive results. My patient population is mostly chronic illness and infections; and then kids on the autism spectrum – and I’m seeing dramatic improvements in both.

So what the heck are Nrf1 and Nrf2 anyway?

The Nrf2 pathway is a genetic pathway that turns on over 200 genes, many of which are related to detoxification. Switching on these pathways allows our cells to detoxify better, but it also causes a dramatic reduction in oxidative stress. Oxidative stress, aka free radical damage, is a natural byproduct of metabolism – but it is accelerated in chronic health conditions and causes cell damage and even cell death.

Reducing oxidative stress is a key element in anti-aging strategies and disease prevention by reducing damage to the cells, but it’s also a key consideration in chronic health issues – injury and inflammation both contribute to oxidative stress.

Nrf2 also boosts our body’s own glutathione production – up to 300%. Glutathione is our master antioxidant to quell free radical damage, especially in the brain where the majority of oxygen is consumed. It also participates in phase 2 liver detoxification and is a natural heavy metal chelator.

Nrf2 allows for healthy gene expression. We see a lot about methylation defects and other genetic deficits. Historically it was thought that whatever our genes were, we were stuck with them. Now, through the field of epigenetics, we know that we can influence how our DNA is transcribed to RNA and finally into the actual proteins that make up our body. Nrf2 influences this healthy gene regulation.

Food can do that too- but not many of us eat enough of those healthy antioxidant foods consistently to make a lasting impact.

By taking 1 tablet a day of a Nrf2 activator, we can keep those pathways open and working well consistently.

Nrf1 is also hugely impactful. Nrf1 synegizers work on the mitochondria, which are the powerhouses of the cell. When the mitochondria are damaged, overridden with toxins, or challenged by the demands of chronic illness, there is less ATP being produced. ATP is our energy currency – without it we can experience chronic fatigue, and we also don’t have the fuel that is needed to drive all our other biochemical processes.

So how does this look in reality?

The Nrf2 Synergizer is a formula made up of five herbs in very specific amounts and ratios. It is a patented formula with 24 peer-reviewed studies on Pubmed (the government’s health/medical research database)

The Nrf 1 Synergizer is a combination of micronutrients that work to promote mitochondrial health.

I also combine these two with another Nrf2 activation formula in a drink mix that provides sustained energy and mental clarity.

It’s not a lot of pills and potions to take each day, and the profound shifts I see in patients is fantastic –

  • Better energy
  • Less inflammation
  • Clearer mind
  • Less discomfort
  • Accelerated ability to heal from chronic infections and toxicities
  • More balanced nervous system
  • Healthier moods
  • In kids – better mental focus, calmer behavior, healthier neurological development

Some people see improvement right away, and for others it takes a while. Remember, this cellular damage did not happen overnight and can take time to repair.

If you would like to learn more about Nrf1 and Nrf2, just drop me a line and I’ll get you added to a private education group that contains a ton of information. In there are modules on a variety of health conditions including Lyme disease, autism spectrum disorders, autoimmune conditions and the like. There’s even one on the benefits of Nrf2 activators in dogs, cats and horses. You can also read more about this patented product, and find ordering information, here.

I look forward to sharing more information with you on this along the way. To me it truly is the forefront of medicine and the way of the future.